In mathematical programming we have a notion of efficient frontier for a multiobjective problem that can help produce tools for the team making these trade offs. I expect wonderful cross fertilization from math programmers watching how real decision makers make these trades. Technology transfer is a two-way street.

The decision makers will want to know which design variables most influence which trades. They will want some notion of how the merit measures change globally with the most important variables.

In fact, it is common that the different disciplines involved in these trade offs will have their own simulations that must be coupled together to have a meaningful simulation based tool.